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QG, MDW, JV and PAS provided critical discussion and revision of the article for intellectual content, and approved the final version of the manuscript

In other cases, you select the amount of medication to be injected

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The hallmark of OA is pathological changes of the joint structure, such as cartilage erosion and synovial inflammation

370 Accordingly, multiple strategies are being developed to circumvent or delay resistance, including rational drug combinations, novel therapeutic agents, microbiome interventions, adaptive treatment regimens, and advanced delivery systems (Fig

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